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Barbara Helfrich Selected Research

CU201

5/2002Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents.
4/2002Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines by a "biased agonist" mechanism.

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Barbara Helfrich Research Topics

Disease

8Lung Neoplasms (Lung Cancer)
01/2006 - 02/2002
6Neoplasms (Cancer)
12/2002 - 03/2002
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2013 - 02/2002
2Prostatic Neoplasms (Prostate Cancer)
12/2002 - 04/2002
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
05/2002 - 04/2002
1Breast Neoplasms (Breast Cancer)
05/2002
1Inflammation (Inflammations)
04/2002
1Neoplasm Metastasis (Metastasis)
03/2002
1Polyps
02/2002
1Colorectal Neoplasms (Colorectal Cancer)
02/2002

Drug/Important Bio-Agent (IBA)

4Bradykinin Receptor AntagonistsIBA
05/2004 - 04/2002
3BradykininIBA
12/2002 - 04/2002
3NeuropeptidesIBA
05/2002 - 04/2002
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2002 - 04/2002
2CU201IBA
05/2002 - 04/2002
2Antineoplastic Agents (Antineoplastics)IBA
05/2002 - 02/2002
2sulindac sulfone (exisulind)IBA
03/2002 - 02/2002
2Docetaxel (Taxotere)FDA Link
03/2002 - 02/2002
1Anaplastic Lymphoma KinaseIBA
11/2013
1ErbB Receptors (EGF Receptor)IBA
01/2006
1Histone Deacetylase InhibitorsIBA
01/2006
1Gefitinib (Iressa)FDA Link
01/2006
1Cadherins (E-Cadherin)IBA
01/2006
1Peptides (Polypeptides)IBA
12/2002
1Hormones (Hormone)IBA
12/2002
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2002
1Metalloproteases (Metalloproteinases)IBA
12/2002
1Tetrazolium SaltsIBA
05/2002
1GemcitabineFDA Link
05/2002
1Membrane Proteins (Integral Membrane Proteins)IBA
05/2002
1Trastuzumab (Herceptin)FDA Link
05/2002
1Monoclonal AntibodiesIBA
05/2002
1Proteins (Proteins, Gene)FDA Link
05/2002
1Cell Surface ReceptorsIBA
04/2002
1Substance PIBA
04/2002
1SulfonesIBA
03/2002
1EnzymesIBA
03/2002
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
03/2002
1Sulindac (Copal)FDA LinkGeneric
03/2002
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
03/2002
1taxaneIBA
03/2002
1Cyclic GMPIBA
03/2002

Therapy/Procedure

3Therapeutics
11/2013 - 04/2002
1Chemoprevention
02/2002
1Drug Therapy (Chemotherapy)
02/2002